Andrés Santos is full professor at the Electronic Engineering Department of the Universidad Politécnica de Madrid and a scientist in the Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine. He is the director of the Biomedical Image Technologies research group and the coordinator of the BioTech-UPM technological initiative. His research is oriented to finding technological solutions to actual clinical or biological relevant problems, especially with the aim of providing early diagnosis or therapy monitoring. The main contributions have been in the field of acquisition and analysis of biomedical images, always emphasizing the testing and validation of the proposed solutions with clinical teams. Some results have been the proposal and validation of tools based on the registration of cardiac image sequences to aid in the early diagnosis of cardiovascular diseases, tools to localize epileptic focus in epilepsy surgery planning, systems to aid in intraoperative radiotherapy planning, to aid in the processing of diffusion MRI and in contrast-enhanced MRI.